APOKYN (apomorphine hydrochloride injection) is used as needed to treat off-episode motor symptoms, such as muscle stiffness, slow movements, and difficulty starting movements, in people with advanced Parkinson's disease (PD). It is used in addition to oral PD medicines.

Important Safety Information
APOKYN can cause severe nausea and vomiting, and your healthcare professional will usually prescribe a certain medicine called Tigan^®* to help prevent or minimize these effects.

APOKYN may lower blood pressure and cause dizziness and fainting, especially when starting treatment or if the dose is increased. You should not get up too fast from sitting or after lying down to minimize these problems.

Some patients may get sleepy during the day or fall asleep without warning during activities of daily living. Until it is known how APOKYN affects you, you should not drive a car or operate machinery.

Be sure to inject APOKYN under the skin, not into a vein.

*Tigan (trimethobenzamide hydrochloride) is a registered trademark of Monarch Pharmaceuticals, Inc.